News

Yesterday Jurrian de Kanter, PhD student of the Van Boxtel group, defended his thesis entitled: "Finding the hidden patterns: single-cell comics to reduce late effects" cum laude. We want to congratulate him with this great achievement!

Co-culture of intestinal organoids with a colibactin-producing pks+ E. coli strain (EcC) revealed mutational signatures also found in colorectal cancer (CRC).

Ruben, has been awarded an NWO Vici grant. With the prestigious grant, Van Boxtel can further expand his research line into the late effects of childhood cancer and how these are reflected at a molecular cell level.

Just before Christmas on December 21st, our PhD student Flavia Peci defended her thesis "Genomic Safety of Transplantation; characterising the Mutational Consequences of Treatment in Hematopoietic Stem Cells".

Tuesday our PhD student Eline Bertrums defended her thesis defence entitled: "The Clonal Dynamics underlying the genesis and regression of myeloid disorders", with cum laude.

In our lab we developed the computational PTA Analysis Toolbox (PTATO) that can effectively filter artifacts from PTA-based WGS data, enabling accurate analyses of somatic mutations in single cells at nucleotide resolution.